Dentacare - Chemical genetic discovery of targets and anti-targets for cancer polypharmacology

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The future of precision cancer therapy might be to try everything

Researchers are blasting patients’ cancer cells with dozens of drugs in the hope of finding the right treatment.

An analysis of genetic heterogeneity in untreated cancers

by Johannes G Reiter, Marina Baretti, Jeffrey M Gerold, Alvin P Makohon-Moore, Adil Daud, Christine A Iacobuzio-Donahue, Nilofer S Azad, Kenneth W Kinzler, Martin A Nowak and Bert Vogelstein